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Corrositex Instruction Manual-(PDF)
This manual is password Protected. Please contact InVitro International
in Irvine, CA. for a password.
Corrositex is an invitro test that determines
chemical corrosivity and permits assignment of Packing Group classification
for Class 8 corrosives. This test replaces the rabbit test of dermal
corrosivity by providing a reliable means of mimicking this test.
The proprietary core technology of the Corrositex
test is based upon a biomembrane and chemical detection system,
which becomes colored when exposed to potentially corrosive substances.
Because it will save you time and money.
- Time Savings: Unlike animal testing that can take 2 to 4 weeks,
Corrositex testing can provide a Packing Group
determination in as little as 3 minutes and no longer than 4
hours.
- Cost Savings: In a recent evaluation, one customer saved up
to $50,000 annually, in shipping costs, for a single compound
when using the Corrositex test to define the
Packing Group instead of relying on pH. In addition to the reduction
in shipping charges, additional cost savings are found in the
areas of workplace safety and MSDS development.
Regulatory Acceptance. Following is a list of agencies that accept Corrositex.
This list continues to grow as regulatory bodies look for more accurate,
cost-effective and humane testing methods. Copies provided upon
request.
- Department of Transportation - DOT-E 10904
- Original exemption granted April 28, 1993
- DOT Permit #10904, 5/30/'06 expiring 4/30/2010
- Renewals granted:
- March 22, 1995
November 30, 1997
January 12, 1999
December 12, 2000
September 20, 2002
July 19, 2004
- Consumer Product Safety Commission (CPSC)
- Formal Acceptance, NIEHS press release dated 3/21/00
- European Centre for the Validation of Alternative Methods (ECVAM)
- 12/2002
- EU/OECD
- Approval July 19, 2006
EPA Federal Register / Vol. 60, No. 142 Dermal Corrosion
Method 1120 June 13, 1997
Formal Acceptance, NIEHS press release dated 3/21/00
- Food & Drug Administration (FDA)
- Formal Acceptance, NIEHS press release dated 3/21/00
- International Air Transportation Association (IATA)
- Letter of acceptance dated December 17, 1993
- National Institute of Environmental Health Sciences (NIEHS)
- Endorsement dated 6/22/99
- Occupational Safety and Health Administration (OSHA)
- Letter of Interpretation dated March 3, 1994
- Formal Acceptance, NIEHS press release dated 3/21/00
- Transport Canada - Permit For Equivalent Level of Safety
SU 4483
- Original approval 8/14/96
- Additional renewal 9/18/98
- Additional renewal 1/15/01
Full Draize Replacement Acceptance 3/5/02
-
 The Corrositex
testing system consists of a glass vial filled with a chemical
detection fluid capped by a proprietary bio-barrier membrane,
which is designed to mimic the effect of corrosives on living
skin.
As soon as the corrosive sample destroys this bio-barrier, the
fluid below changes color or texture. Users simply record the
time it takes for the sample to break through the membrane. Then,
depending on their needs, they can assign the proper U.N. Packing
Group classification for U.S. DOT or EPA compliance, or use the
data as a ranking tool or to substantiate marketing claims.
InVitro International
17751 Sky Park East, Suite G
Irvine, CA 92614
800-2-INVITRO (800-246-8487)
949-851-8356 (International callers)
949- 851-4985 Fax
invitro@invitrointl.com
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